Balanced translocations are present in what percentage of couples with recurrent pregnancy loss?

Balanced translocations are structural chromosomal rearrangements where segments of chromosomes are swapped without any gain or loss of genetic material. In the context of couples experiencing recurrent pregnancy loss, balanced translocations can play a significant role in embryos developing with chromosomal abnormalities, which may lead to miscarriage.

Research shows that approximately 5-10% of couples who have experienced recurrent pregnancy loss carry balanced translocations. This risk reflects the underlying genetic factors that can contribute to the increased likelihood of miscarriages in these couples, with balanced translocations potentially disrupting normal genetic inheritance and leading to dysfunctional embryos.

The other options represent percentages that are either too low or too high based on current data. Balancing the risks and understanding the genetic implications for couples experiencing multiple pregnancy losses can guide genetic counseling and further investigations into their reproductive health.