For BRCA2 mutation carriers, what is the likelihood of developing prostate cancer?

For BRCA2 mutation carriers, research indicates that they have a significantly increased risk of developing prostate cancer compared to those without such mutations. While estimates of risk can vary, it's generally accepted that up to 60% of male BRCA2 mutation carriers will develop prostate cancer by age 70. This elevated risk is associated with the role of the BRCA2 gene in DNA repair. When this gene is mutated, it can lead to accumulation of genetic errors that contribute to the initiation and progression of cancer, including prostate cancer.

The other options present likelihoods that don't align with established data for BRCA2 mutation carriers specifically. While there may be studies showing varying risk percentages, the most widely cited estimates reflect that the risk reaches around 60%. Thus, the correct answer accurately reflects the consensus from genetic studies and clinical observations concerning BRCA2 and its correlation to prostate cancer risk.