Fryns Syndrome is primarily caused by mutations in which type of gene inheritance?

Fryns syndrome is primarily caused by mutations in genes that are inherited in an autosomal recessive manner. This means that both copies of a gene in an individual must be mutated for the syndrome to manifest. In the case of autosomal recessive disorders, an individual who has one normal and one mutated copy of the gene (carriers) does not typically show symptoms of the condition. Only when both copies are affected does the individual exhibit the clinical features of the syndrome, which may include a distinctive facial appearance, congenital anomalies, and developmental delays, among others.

The autosomal recessive inheritance pattern is important in understanding the risk of the condition occurring in families, as it guides genetic counseling and informs family members about their carrier statuses and the likelihood of having affected offspring. Given this understanding of Fryns syndrome, the correct answer appropriately reflects its genetic basis.