How many live births are affected by Klinefelter Syndrome?

Klinefelter Syndrome is a genetic condition that occurs in males when they have at least one extra X chromosome, resulting in a karyotype such as 47,XXY. The prevalence of Klinefelter Syndrome is estimated to be around 1 in 600 live male births. This statistic reflects the condition's relatively common occurrence compared to other chromosomal abnormalities. Given that Klinefelter Syndrome often goes undiagnosed or is diagnosed later in life, the actual prevalence during live births may be underrepresented in clinical settings.

The statistics in the other options represent different estimates of various conditions or may not be accurate for Klinefelter Syndrome specifically. Thus, the figure of 1 in 600 live births is a well-supported estimate and is widely accepted in genetic literature.