What characteristic feature is associated with Gorlin Syndrome?

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Gorlin Syndrome, also known as Nevoid Basal Cell Carcinoma Syndrome, is characterized by the presence of specific physical and clinical features. Among these, palmar pits and jaw cysts stand out as hallmark manifestations. Palmar pits are small depressions located on the palms of the hands, a distinctive trait often noted during clinical examinations. Jaw cysts, particularly odontogenic keratocysts, frequently occur in individuals with Gorlin Syndrome and can lead to dental complications, making their recognition crucial for diagnosis.

The other features mentioned in the other options, while related to different conditions or syndromes, are not characteristic of Gorlin Syndrome itself. For instance, retinal cancers and renal cell carcinoma (RCC) may be associated with other genetic syndromes, but they are not primary features of Gorlin Syndrome. Similarly, renal cysts can occur in various genetic conditions, including renal cystic diseases, but they do not define Gorlin Syndrome. Pineoblastoma is a rare tumor associated primarily with certain syndromes like familial retinoblastoma and is not a recognized feature of Gorlin Syndrome.

Thus, palmar pits and jaw cysts are the definitive characteristic features used to identify and understand Gorlin Syndrome, making it the correct answer

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