What condition is characterized by syndactyly of at least 3 fingers?

Apert Syndrome is characterized by syndactyly of at least three fingers, along with other notable craniofacial dysmorphisms and limb malformations. This condition is part of a group of disorders known as craniosynostosis syndromes, which occur due to mutations in the FGFR2 and FGFR1 genes. In addition to syndactyly, individuals with Apert Syndrome often exhibit fusion of other digits (partial or complete), while also having distinctive craniofacial features such as a high forehead, a fused brow, and varied facial asymmetries.

Syndactyly itself is a broader term that refers to the condition of having fused fingers or toes, but it doesn't specify the number of digits involved. It can occur in isolation or as part of a larger clinical picture. Crouzon Syndrome primarily results in craniosynostosis and has specific facial features but is not specifically characterized by syndactyly of three or more fingers. Micromelia refers to the abnormal smallness of limbs and is not directly related to finger fusion as seen in syndactyly.

Thus, the features associated with Apert Syndrome, particularly the prominent syndactyly involving at least three fingers, makes it the correct answer in this context.