What does PGT-SR stand for?

PGT-SR stands for Preimplantation Genetic Testing for Structural Rearrangement. This type of genetic testing is used to analyze the chromosomal composition of embryos created through in vitro fertilization (IVF), specifically focusing on identifying structural rearrangements (such as translocations, inversions, deletions, or duplications) in chromosomes.

By examining these structural abnormalities prior to implantation, clinicians can better assess the viability of the embryos and reduce the risk of inherited disorders that are associated with such rearrangements. This differs from other forms of preimplantation genetic testing, which may target different genetic issues, such as aneuploidy (abnormal number of chromosomes) or specific Mendelian disorders. PGT-SR plays a crucial role in providing information that can help patients make informed decisions about embryo selection for a successful pregnancy.