What is the main consequence of clavicular hypoplasia in Cleidocranial Dysplasia?

The main consequence of clavicular hypoplasia in Cleidocranial Dysplasia is the resulting narrow, sloping shoulders. This is significant because the clavicles (collarbones) play an essential role in shoulder width and stability. In individuals with this condition, the underdevelopment or absence of the clavicles restricts the normal outward development of the shoulders, leading to a characteristic appearance. This physical manifestation can affect the overall posture and sometimes the ability to raise the arms fully, further emphasizing how crucial the clavicles are for typical anatomical function and aesthetics.

While other consequences such as excessive teeth growth, delayed closure of cranial sutures, and heightened risk of fractures are associated with Cleidocranial Dysplasia, they do not directly stem from clavicular hypoplasia in the same manner that shoulder shape does. The increase in teeth number is due to dental anomalies, cranial suture closure varies individually and may not be impacted solely by clavicle issues, and while individuals can possess increased fracture risk due to bone structure differences, this is not the primary or most visually apparent consequence like the shoulder appearance is.