What test is suggested if an IgM positive result is detected for CMV?

When an IgM positive result for cytomegalovirus (CMV) is detected, it typically suggests a recent or active infection, which can have implications during pregnancy. In such cases, amniocentesis with PCR (polymerase chain reaction) testing is often recommended to confirm the presence of CMV in the amniotic fluid.

Amniocentesis allows for direct testing of the fetus and is more specific than other tests for determining whether the fetus is infected with the virus. PCR testing can detect the viral DNA in the amniotic fluid, providing crucial information about the risk of congenital CMV infection and its potential impact on fetal development. This test is particularly useful because it can detect the virus even when symptoms are absent, allowing for early intervention if needed.

Other options, while they may serve certain diagnostic purposes, do not directly address the need for identifying CMV presence in the fetus as effectively as amniocentesis with PCR does. For instance, an ultrasound scan can assess fetal health and development but cannot directly confirm CMV infection. A cervical biopsy would be irrelevant in this situation, as it focuses on cervix pathology rather than viral presence in the fetus. A blood antigen test may assist in diagnosing CMV