Which characteristic feature is NOT associated with Werner Syndrome?

In the context of Werner Syndrome, the characteristic features include a set of symptoms that are typically associated with aging but manifest at a much younger age. The condition is a rare, autosomal recessive disorder caused by mutations in the WRN gene, which plays a crucial role in DNA metabolism and repair.

Premature cataracts are a common manifestation of Werner Syndrome, with individuals often developing cataracts in their twenties or thirties. Short stature is also a notable feature, where affected individuals tend to be significantly shorter than average. Gray hair is another characteristic, as individuals with this syndrome may experience graying of hair at a much earlier age than typical.

Insulin resistance is not a hallmark feature of Werner Syndrome. While metabolic issues can arise in various genetic syndromes, Werner Syndrome is more specifically associated with physical aging manifestations rather than metabolic disorders like insulin resistance. This distinction makes the absence of insulin resistance a correct choice when identifying which feature is not associated with Werner Syndrome.