Which condition is associated with the truncus arteriosus finding in ultrasound?

The association of truncus arteriosus with 22q11.2 deletion syndrome, also known as DiGeorge syndrome, is well established in medical literature. Truncus arteriosus is a congenital heart defect where a single arterial vessel arises from the heart, which normally splits into the aorta and pulmonary arteries. This condition is commonly associated with genetic syndromes, particularly those involving chromosome 22.

In the case of 22q11.2 deletion syndrome, the abnormalities in cardiac development caused by genetic mutations can lead to various structural heart defects, including truncus arteriosus. The syndrome is characterized by a variety of phenotypic manifestations, including immunodeficiency, hypoparathyroidism, and facial dysmorphisms, in addition to the cardiovascular anomalies.

The other options present conditions that have different associations. For example, Meckel Gruber syndrome is primarily linked to renal and neurological abnormalities rather than cardiac defects. Holt-Oram syndrome is associated with issues affecting the heart and upper limbs but does not have a strong connection to truncus arteriosus specifically. Stickler syndrome is connected to joint problems and eye issues, rather than the specific heart defects seen in 22q11.2 deletion syndrome. Thus, the presence