Which condition is associated with heart and arm anomalies detected by ultrasound?

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The condition associated with heart and arm anomalies detected by ultrasound is Holt-Oram syndrome. Holt-Oram syndrome is a genetic disorder characterized by congenital heart defects and upper limb malformations, which can include issues such as absent or poorly formed arms. The heart defects often involve the septum or other structural anomalies.

In prenatal diagnosis, ultrasound is a critical tool for detecting these types of anomalies. The presence of both cardiac defects and limb anomalies in a developing fetus would point towards Holt-Oram syndrome, allowing for further genetic counseling and management considerations.

Other conditions, while they may present with various anomalies, do not specifically manifest both heart and arm anomalies in the combination characteristic of Holt-Oram syndrome. For instance, Beckwith-Wiedemann syndrome primarily involves overgrowth and organomegaly, Meckel-Gruber syndrome is associated with renal cysts and neural tube defects, and Stickler syndrome is characterized by ocular, auditory, and skeletal abnormalities, but not typically with the specific combination of heart and arm anomalies that define Holt-Oram. Thus, Holt-Oram syndrome is the most appropriate answer for the described condition in the question.

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