Which genetic condition features wide-set eyes and flattened cheekbones?

The description of wide-set eyes and flattened cheekbones aligns with the features observed in Muenke Syndrome. This genetic condition is a result of mutations in the FGFR3 gene, leading to various craniofacial abnormalities, including the characteristic dysmorphic features. People with Muenke Syndrome typically present with distinct facial traits, such as hypertelorism (widely spaced eyes) and other midfacial hypoplasia, which can result in a flattened appearance of the cheekbones.

Understanding the unique phenotypic features of genetic disorders is essential for the diagnosis and management of these conditions. Other syndromes listed may have their own specific features but do not primarily highlight the combination of wide-set eyes and flattened cheekbones to the same degree as Muenke Syndrome. This distinction is critical in the clinical assessment and recognizes the need for accurate identification of genetic conditions based on characteristic physical features.