Which is a significant risk factor for developing complications from Zika virus infection?

Traveling to endemic areas is a significant risk factor for developing complications from Zika virus infection because the virus is primarily transmitted through the bite of infected Aedes mosquitoes, which are found in specific geographic regions. Individuals who travel to areas where Zika virus is prevalent are at a higher risk of being bitten by these mosquitoes and contracting the virus. This increases the likelihood of experiencing the health complications associated with Zika, particularly for pregnant women, as Zika infection during pregnancy can lead to severe birth defects such as microcephaly and other neurological issues in the fetus.

In contrast, while maternal obesity and age over 35 can have implications for pregnancy and health in general, they are not specifically significant risk factors for Zika complications. Additionally, a family history of genetic disorders does not influence the risk of developing complications from a viral infection like Zika. Hence, the correct choice highlights the direct link between travel to areas where the Zika virus is active and the possibility of contracting the infection, which is crucial for understanding risk management and prevention strategies.