Which syndrome does not present with corneal clouding?

Hunter Syndrome is classified as a mucopolysaccharidosis (MPS) caused by the deficiency of the enzyme iduronate-2-sulfatase, leading to the accumulation of glycosaminoglycans in the body. One of the key clinical features of Hunter Syndrome is the absence of corneal clouding, which differentiates it from other syndromes in the same category, such as Hurler and Morquio syndromes, where corneal clouding is commonly observed due to the accumulation of these substances in the cornea.

In contrast, Hurler Syndrome, also a mucopolysaccharidosis, typically presents with corneal clouding as one of its hallmark features, along with other systemic manifestations such as skeletal abnormalities and developmental delays. Gaucher Disease, while primarily affecting the liver, spleen, and bone, does not usually present with corneal clouding either; however, its classification and symptomatology differ from Hunter Syndrome. Morquio Syndrome, another type of MPS, is characterized by corneal clouding as well, along with skeletal deformities, further solidifying Hunter Syndrome's unique clinical pathway regarding corneal health.

Thus, Hunter Syndrome stands out as the condition from the options provided that does not exhibit cor