Which ultrasound finding is least likely to be associated with maternal health issues?

The finding of a short femur is least likely to be associated with maternal health issues. In the context of prenatal ultrasound, a short femur may be indicative of certain fetal conditions such as skeletal dysplasias or growth restriction. However, it is not typically linked directly to maternal health issues.

In contrast, other findings like holoprosencephaly, duodenal atresia, and increased nuchal fold thickness often have more direct associations with maternal health. Holoprosencephaly can be linked with maternal diabetes or certain environmental exposures. Duodenal atresia is commonly associated with conditions like Down syndrome which may relate back to maternal age and health. Increased nuchal fold thickness is often considered in the context of chromosomal abnormalities and can reflect maternal factors as well.

Thus, while every ultrasound finding requires thorough evaluation, particularly the context of maternal health, a short femur stands out as being less directly tied to maternal issues compared to the other findings listed.